Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and ...

Opioid receptors are proteins in the nervous system that interact with opioids. Opioid receptors are part of the endogenous opioid system. This is the body’s internal system for regulating pain, ...

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors function in the brain and why they play a central role in pain relief, ...

Kappa-opioid receptor (KOR) agonists represent a promising class of compounds that modulate pain, mood and various neurobehavioural processes. Unlike traditional opioids that primarily target the ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...

Neuropeptide FF (NPFF) is an endogenous peptide that plays a critical role in modulating opioid receptor function. Its dual capacity to influence both opioid-induced analgesia and tolerance has ...

(THE CONVERSATION) Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States’ fight against the opioid crisis. It reverses an opioid overdose nearly ...