Chemotherapy for pediatric acute lymphoblastic leukemia (ALL) induces rapid and durable alterations in cerebrospinal fluid (CSF) metabolism, and a lipid-rich CSF signature measured early in treatment ...
CIDP causes muscle weakness and numbness, among other symptoms. Diagnosing CIDP involves peripheral nervous system testing, cerebrospinal fluid analysis, and imaging. CIDP is an immune-mediated ...
CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.
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