Universal gene‑edited CAR‑T therapies turn donor T cells into off‑the‑shelf cancer treatments, cutting delays and costs while ...

The physical barrier allowed Tpex cells to build up safely inside the tumor without being pushed into full exhaustion by constant contact with cancer cells. When the barrier was removed, using ...

The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and eyes. These barriers are created by cells that are joined tightly together ...

The blood‐testis barrier (BTB) is one of the most specialised barriers in the body, crucial for establishing a protected microenvironment for spermatogenesis. Comprised predominantly of tight ...

Cells in the gut send secret messages to the immune system. Thanks to new research from La Jolla Institute for Immunology (LJI) scientists, we can finally get a look at what they're saying. A new ...

Scientists at Stanford University have uncovered a novel physical mechanism that breast cancer cells use to break out and become invasive. They observed that in addition to established chemical ...

Chinese researchers recently reported a method for improving cancer immunotherapy efficacy by giving T cells—the body's cancer- and infection-fighting white cells—a rest. Cancer immunotherapies such ...

Delivering therapies to the brain remains a major challenge due to the limited permeability of the blood-brain barrier. In a ...

Cell and gene therapies (CGTs) are poised to transform the treatment landscape for a growing number of conditions, but hurdles remain before these innovative medicines can reach their full potential.