Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing ...

Getting a therapeutic gene into the right cell has been one of medicine’s most stubborn problems, especially in the brain and ...

CAR-T-cell therapies are revolutionizing the treatment of blood cancers, and their full potential is still being explored in hundreds of clinical trials. In this therapy, a patient’s own T cells are ...

The immune system provides an integral defense against cancer growth and progression. Activating an anti-tumor immune response relies on several biological steps that can ultimately result in the ...

Researchers show for the first time that engineered human plasma B cells can be used to treat a disease -- specifically leukemia -- in a humanized animal model. The results mark a key step in the ...