Pancreatic cancer is lethal not only because it grows, but because it spreads early and aggressively. New research suggests the tumour can reprogramme surrounding tissue to create physical and ...

Brazilian researchers have found that stellate pancreatic cells produce periostin, which reshapes surrounding tissue and allows tumors to spread more easily, helping explain why the disease is so ...

In which tissues, organisms and systems do divisions enable or enhance infiltration? Is immune infiltration into tumors facilitated by divisions? Are migrating cells attracted to dividing tissue cells ...

How do cells move from A to B through our body to build functional tissues? And how is this process regulated? The answers to these questions are essential – for example, for our understanding of how ...

Cell invasion is a mechanical process in which a migrating cell applies forces causing rupturing and deformation of the tissue. Resistance of tissue to invasion is determined by adhesion strength ...

Low-grade serous ovarian cancer (LGSC), accounts for just 5% to 10% of all epithelial ovarian cancers, but its distinct biology makes it especially challenging to treat. While the origin of this ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

This study presents a valuable finding regarding the role of Arp2/3 and the actin nucleators N-WASP and WAVE complexes in ...

As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.