When pathogens enter our cells as part of an infection, our body will trigger a programmed cell death known as "pyroptosis" as part of an antimicrobial response. This response also plays a role in ...

When injured, cells have well-regulated responses to promote healing. These include a long-studied self-destruction process that cleans up dead and damaged cells as well as a more recently identified ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

New research has updated our understanding of how sugars, known as glycans, help immune cells move into skin in the inflammatory disease, psoriasis. The paper entitled “Leukocytes have a heparan ...

Researchers discover how mitochondria not only produce energy but also influence inflammation. Whether cells in the human body survive or die under stress depends, among other things, on their ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

The class of anti-inflammatory drugs known as TNF-inhibitors has brought relief to many sufferers of rheumatoid arthritis, ...

New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's disease. A research team led by Mount Sinai has uncovered mechanisms of ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...