Researchers developed a way to directly reprogram human glial cells into PV interneurons without passing through a stem‑cell stage.

CAMBRIDGE, MA -- Converting one type of cell to another — for example, a skin cell to a neuron — can be done through a process that requires the skin cell to be induced into a “pluripotent” stem cell, ...

Employing a chemical reprogramming strategy to convert human epidermal keratinocytes into expandable sweat gland cells using six specific chemicals. Upon transplantation into damaged skin tissues in a ...

Human skin cells have been reprogrammed into heart valve cells and then used to successfully transplant a pig heart valve into a rodent, led by the research of a Northeastern University professor. The ...

Life runs on information. In living systems, that information takes two main forms: the genome and the epigenome. The genome stays mostly stable. The epigenome, however, constantly shifts, shaped by ...

For those hoping to cure death, and they are legion, a 2016 experiment at the Salk Institute for Biological Studies in San ...

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos. The ...