Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Some of the signs of aging in human cells originate in the cell nucleus, because the packaged form of DNA changes with age.

The way the body ages could be more resilient than previously thought, a new study suggests. Published in the Journal of the American Chemical Society, the work by researchers at King's College London ...

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable ...

Researchers have unveiled CREsted, a comprehensive software powerhouse. CREsted doesn’t just describe how DNA works; it allows scientists to design entirely new, synthetic enhancers—short DNA ...

Chromatin's structure plays an important regulatory role in DNA template-dependent processes including transcription, replication, recombination, repair, segregation, chromosomal stability, cell cycle ...

A new software package called CREsted, published in Nature Methods, gives researchers an end-to-end workflow for modeling and ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...