Metabolites can inhibit the enzymes that generate them. To explore the general nature of metabolic self-inhibition, we surveyed enzymological data accrued from a century of experimentation and ...

Reply letter to Dr. Wojtasek regarding: Oxidation of flavonoids by tyrosinase and by o-quinones-comment on "Flavonoids as tyrosinase inhibitors in in silico and in vitro models: basic framework of SAR ...

The rise of influenza strains resistant to current flu treatments has drug developers looking for new leads. Hope could come from a new family of inhibitors that may effectively block the flu virus ...