Complement is a subsystem of immunity that's fast acting and disregulated in multiple inflammatory diseases. Inhibition of complement is a young niche that's gonna get lots more attention soon.

Iptacopan is an innovative, first-in-class oral small molecule that reversibly inhibits factor B—a crucial serine protease in the alternative pathway of the complement system. By targeting this point ...

A complement blood test measures how well complement proteins in your blood support immune defense. The complement system helps antibodies fight germs and clear foreign substances. Complement testing ...