Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly, a molecule makes a promising new medicine. Normally, creating better ...

It’s hard to improve on a classic. But Richard Y. Liu was eager to take on that challenge. Cross-coupling reactions, including Suzuki-Miyaura coupling and Buchwald-Hartwig amination, are some of the ...

Using directed evolution, researchers have developed an enzyme that catalyses the formation of biaryl bonds (Nature 2022, DOI: 10.1038/s41586-021-04365-7). This new enzyme makes carbon-carbon bonds ...

A new catalyst strategy developed at Institute of Science Tokyo uses BaSi2 as a support for nickel and cobalt to decompose ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by ...