CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

The Immune Atlas identifies immune signatures in MM, enhancing outcome prediction and guiding personalized therapies by analyzing over 1.3 million single cells from 337 patients.

Stanford University-led researchers report that tumor cells hijack mitochondria from immune cells, reducing anti-tumor immune ...

Encephalitis is an inflammation of the brain that can be caused by infections or autoimmune reactions. Even when patients survive the acute phase, many are left with long-lasting neurological problems ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...