A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

Scientists used a bacterial system called retron to turn DNA into a programmable tool inside living cells, enabling gene ...

DPY30 was identified as a promoter of cancer cell proliferation and tumor survival. Targeting this protein may enhance the ...

When AlphaFold solved the protein-folding problem in 2020, it showed that artificial intelligence could crack one of biology’s deepest mysteries: how a string of amino acids folds itself into a ...

Researchers at The University of Texas MD Anderson Cancer Center have identified an epigenetic target for replication stress, ...

Illustration of fork-MMEJ and BIR pathways in repairing single-ended DNA double-stranded breaks at broken replication forks, highlighting ATR-mediated regulation of the transition between these two ...