Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results, researchers are now watching individual molecules collide with cell ...
A new editorial paper was published in Oncoscience, titled "PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs." While targeted cancer therapy is greatly ...
In this study in silico docking models were employed to investigate the molecular interactions between the receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein, derived from the ...
A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...
Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...
Scientists have developed a drug that potently neutralizes SARS-CoV-2, the COVID-19 coronavirus, and is equally effective against the Omicron variant and every other tested variant. The drug is ...
A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...