DNA, the genetic material compacted in chromosomes, stores information to regulate all the cell processes in the body. Two decades ago, in addition to the widely known Watson-Crick double helix model ...

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

Comparing the impact of nivolumab & ipilimumab combination therapy vs. dabrafenib & trametinib on outcomes in malignant melanoma patients: A global propensity-matched retrospective cohort study. This ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...