MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

It is often assumed that modern humans are no longer evolving. But there is now considerable agreement among scientists that evolution is still affecting our species—and this process is taking place ...

In a new UCLA-led study, investigators shed light on the intricate processes underlying cancer evolution and define the optimal algorithms to analyze the genetic makeup of tumors. Understanding the ...

The present theory offers a unified solution to three closely related evolutionary problems. (1) Why does an evolving population explore only a small fraction of the accessible pathways in genotype ...

From epic poetry to game shows, from Stone Age axes to spaceflight, humans have the most complex cultures of any species on Earth. Since the time of Darwin, scientists have suspected that this culture ...

Some colorful lizards and a mathematical formula from the finance sector have been used to build a new framework to model evolution. Developed by Dr. Simone Blomberg from The University of ...

For over a thousand years, the story of human evolution was simple: Homo sapiens developed in Africa between 200,000 and 300,000 years ago from a single line of forebears. But today, one research has ...

Think of evolution, and you might think of Darwin's finches and natural selection. But according to researchers writing in the journal BioScience, it is not our genes that are determining our current ...

There are a variety of methods that have been established to curtail the spread of infectious disease, from isolation or donning of PPE to prevent human-to-human transmission, to culling infected ...