This patient presented with advanced renal failure in the setting of severe hypocomplementemia, significant eosinophilia, eosinophiluria, and lymphopenia. He had neither proteinuria nor active urinary ...

Overall, of the 390 patients completing pregnancy, 17% had only positive anti-dsDNA, 12% had only hypocomplementemia, 20% had both serologies, and 51% had neither serology at the time of enrollment.

Complement activation is common in patients with systemic lupus erythematosus (SLE), resulting in hypocomplementemia and deposition of complement at sites of tissue damage. The availability of mice ...