Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the GI tract. The two major types of IBD are Crohn's disease (CD) and ulcerative colitis (UC). Whereas in UC inflammation ...

Cellular Innate immunity acts as the body's initial defense against pathogens, including viruses. It represents an evolutionarily ancient system, providing rapid but nonspecific responses to a wide ...

Novel research led by Brazilian scientists describes the immune system's reactions in detail in the first living patient to ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

1 Department of Internal Medicine, Division of Rheumatology, University of New Mexico, Albuquerque, NM 2 Biomedical Research Institute of New Mexico, Albuquerque, NM 3 Department of Molecular Genetics ...

Immunology has transformed humanity’s understanding of oneself and its battle against disease. Inflammation which is a primordial defense mechanism against pathogens, also acts as a double-edged sword ...

Clinical research has long focused on ways to harness the actions of the immune system. From vaccines to immunotherapies, researchers have used their knowledge of the immune system to develop ...

Background Exacerbations are major causes of morbidity in individuals with chronic respiratory diseases such as chronic ...

From babyhood to adulthood, the bacteria and fungi on your skin help train your immune system—but when that balance tips, chronic inflammation can follow. This new review reveals how and why. Study: ...