EPFL scientists have now discovered that a DNA-sensing mechanism of the innate immune system - which is pivotal for the immediate defense against pathogens -- controls cellular senescence. The work is ...
The innate immune response constitutes the body’s first line of defence against pathogens, utilising a network of pattern recognition receptors (PRRs) and signalling molecules to detect and neutralise ...
In a study published online in Cell, scientists at UCSF QBI, University College London and the Icahn School of Medicine at Mount Sinai reported breakthrough findings on convergent evolutionary ...
In a recent review published in Nature Reviews Immunology, researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field. Galectins comprise ...
Scientists at UCSF QBI, University College London and the Icahn School of Medicine at Mount Sinai reported breakthrough findings in a study published Sept. 21, 2023, on convergent evolutionary ...
Group 2 innate lymphoid cells (ILC2s) of the immune system are involved in allergic diseases. But currently, therapy targeting ILC2s is not available. Now, researchers have identified a novel ...
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate: Building resilience against pathogens
The hydrolysis of endosomal PI(4,5)P2 in the intestine of C. elegans is mediated by RAB-10, a mechanism vital for the establishment of immunity against pathogens. Endosomes manage key metabolic ...
Trained immunity enhances innate immune responses, yet a Western lifestyle may lead to maladaptive trained immunity and drive ...
Research from Radboud university medical center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of ...
Nipah virus does not just infect the body, it disrupts immune defences at multiple levels, suppressing early antiviral responses and triggering harmful inflammation.
Researchers highlight how exercise and dietary strategies may complement immunotherapy by improving immune function, tumour perfusion, and quality of life.
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