In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

The GPCRact AI model goes beyond AlphaFold3 by predicting whether drugs functionally activate G-protein-coupled receptors ...

Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a ...

Peptide-based molecules have increasingly been positioned not merely as isolated biochemical entities, but as conceptual instruments through which ...

Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality. In severe cases, bacterial invasion and sustained immune responses ...