Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

The liver, located in the upper right side of the abdomen, is the body’s largest organ and one of the most important. The liver performs hundreds of vital functions, including converting nutrients ...

A risky but often lifesaving surgery that removes damaged parts of the small intestine can leave patients facing a new threat ...

More than 10,000 Americans are waiting for a liver transplant. Many more never make the list, because they are too sick to ...

The liver of a 56-year-old male patient was severely damaged. Chronic hepatitis B, compounded by alcoholic liver injury, ...

Hepatitis B is one of the most widespread viral infections in the world, with hundreds of millions of people living with it today. Caused by the hepatitis B virus (HBV), this condition primarily ...