The completion of mitosis is governed by the dephosphorylation of cyclin-dependent kinase (Cdk) substrates and by the ubiquitination of anaphase-promoting complex (APC) substrates. The order in which ...

In the process of replicating themselves, cells have another choice: do they want to make an identical copy and be left with two cells? Or do they want to make four “half-copies”, in preparation for ...

The primary mechanism by which organisms generate new cells is through cell division. During this process, a single "parent" cell will divide and produce identical "daughter" cells. In this way, the ...

Figure 1: Mto1/2 complex puncta disappear during mitosis. To confirm that Mto2 hyperphosphorylation and disruption of the Mto1–Mto2 interaction were not artefacts of an extended mitotic arrest, we ...