A mutation in the TDP-43 protein reduces the viability of motor neurons without triggering protein clumps, researchers found.
Astrocytes in the cerebellum trigger a shift in GABA signaling during late adolescence, enabling adult-level motor coordination.
Jing Wu receives funding from Karolinska Institutet’s Research Foundation. The scientist Stephen Hawking lived with amyotrophic lateral sclerosis (ALS), the most common type of motor neurone disease, ...
The test was developed by researchers at the US-based not-for-profit Brain Chemistry Labs, who analysed 788 blood samples – roughly half from patients with the disease and half from people without it.