A gene therapy candidate extended survival in a mouse model of SMARD1, supporting its testing in a clinical trial for this ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...

Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research. Mice don't get ...

A paper in <em>Nature Methods</em> this week establishes a scale that can estimate how much pain mice are feeling based on facial expressions.