Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with no cure and limited treatment options.

New experiments reveal how astrocytes tune neuronal activity to modulate our mental and emotional states. The results suggest ...

Working with week-old zebrafish larva, researchers decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze. The study found that a simplified artificial ...

Each brain is unique, not only in its connections but also in the molecular composition of its neurons, particularly ion channels. Despite their variability, the brain functions reliably -- a paradox ...

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to microglia and exposing a critical vulnerability in brain protein maintenance ...

Synaptic transmission is an energy hog. It requires neurons to tap ATP reserves to respond to incoming signals. How do they pull this off, thousands to millions of times per day? A new study ...

BOSTON, Mass. (July 15, 2024)—A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children’s Hospital has revealed that an immune protein impacts neuronal protein synthesis in ...

The innate immune protein C1q seems to have a thing for neurons. Already implicated in synaptic pruning by microglia, now it is reported to also slow down protein production in neurons of the aging ...

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due ...

Working with week-old zebrafish larva, researchers at Weill Cornell Medicine and colleagues decoded how the connections formed by a network of neurons in the brainstem guide the fishes' gaze. The ...