aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

The kidney's proximal tubule reabsorbs water, glucose, ions and other small molecules from the urine and thus maintains the ...

This is a preview. Log in through your library . Abstract Our previous studies of microperfused single proximal tubule showed that flow-dependent Na⁺ and HCO₃⁻ reabsorption is due to a modulation of ...

Renal cell carcinoma, also called hypernephroma, is a cancer of the kidneys that forms in the proximal convoluted tubule. In the UK, it is the eighth most common cancer among adults, affecting 9,300 ...

Congenital urinary tract obstruction is the single most important cause of childhood chronic kidney disease. We have previously demonstrated that human and primate fetal obstruction impairs the ...