More good news in the battle against opioid addiction. Scientists have reopened research into a class of opioids that were ...

Is there a safe opioid? Scientists discovered DFNZ, a high-potency nitazene that relieves pain without the risk of overdose ...

National Institutes of Health researchers have identified a compound called N-desethyl-fluornitrazene, or DFNZ, that ...

Using a long-abandoned class of opioids as their starting point, scientists have discovered an opioid painkiller that doesn't ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off ...

Suzetrigine prevents pain signals from reaching the brain and doesn't give an opioid-like high, making it non-addictive—but it's expensive. Reading time 2 minutes To treat acute pain, doctors in the U ...

One year after FDA approval, Journavx (suzetrigine) offers a promising non-opioid option for acute pain, but experts have concerns about long-term safety, opioid-sparing effects and real-world use.

The clinics that control methadone are driving people out of treatment and back to a toxic supply of street drugs.

With the rise of obesity drugs a pair of Penn State researchers set out to answer a question: could drugs aimed at weight loss help battle opioid addiction? Researchers Dr. Patricia Grigson and Dr.

Researchers have developed a compound that relieves pain in mice but doesn't affect the brain, thereby avoiding mind-altering side effects and abuse potential. The custom-designed molecule, derived ...

The two million people who suffer from opioid use disorder are rarely prescribed the best drug to treat them, but physicians at UT Southwestern and local nonprofit Youth 180 are getting the word out ...

Proposals to ban or regulate kratom, a plant-based substance sold in gas stations, convenience stores and vape shops, are making headlines in local newspapers across the United States. But as ...