New research from the University of St Andrews has discovered a crucial piece in the puzzle of how all animals with a spine—including all mammals, fish, reptiles and amphibians—evolved. In a paper ...

Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...

Australian researchers have uncovered a crucial new mechanism that helps explain how the heart's major blood vessels form during early development, and how disruptions to this process can lead to ...

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Aging immune cells may be sabotaging the body from within. Researchers found that macrophages produce a protein that locks ...

Instead of killing bacteria, scientists found a way to gently guide gut microbes to produce compounds linked to longevity and healthier aging.

A deep dive into the scientific shift toward multi-target obesity therapeutics and its implications for metabolic health and disease prevention.