Nearly seven years ago, MIT scientists mapped the molecular structure of proteins in spider silk threads onto musical theory to produce the "sound" of silk in hopes of establishing a radical new way ...

Figure 1: Constraining peptide conformation and reducing the number of disulfide bond isomers in disulfide-rich polypeptides by applying Dtaas. Dtaas could also potentially be applied in the directed ...

Proteins are made of amino acid chains, or polypeptides. Amino acids have a basic backbone made of an amino group and a carboxyl group, and differ in their side-chains. These polypeptide chains of ...

The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. Scientists have used cryo-electron ...

Proteins, we hear you loud and clear. A group of researchers from Massachusetts Institute of Technology (MIT) devised an artificial-intelligence (AI)-based approach to translate each of the 20 amino ...

One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain.

Mutations can occur on several levels, including genetic, but can also take the form of amino acid replacements during protein synthesis. Amino acid replacements can be deleterious, neutral, or ...

Only 20 standard amino acids are used to build proteins, but why exactly nature "chose" these particular amino acids is still a mystery. One step toward solving this is to explore the "amino acid ...