Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing ...

Scientists have unveiled two major CRISPR breakthroughs: a ThermoCas9 variant that can distinguish and cut tumor DNA while sparing healthy cells, and a retron-based editing system adapted from E. coli ...

Antibiotics usually save lives—but against some bacteria, they can make things worse. That’s the case with the Shiga toxin–producing Escherichia coli, where bacterial death releases a flood of a ...

When scientists discovered how bacteria protect themselves against viral invaders, called phages, in the early 2000s, little did they know they'd stumbled upon a revolutionary tool researchers could ...

Using laboratory-evolved versions of CRISPR-associated transposases (CASTs) from bacteria, scientists at the Broad Institute and Columbia University were able to insert healthy genes into human cells ...

The global rise in antibiotic resistance is making bacterial infections harder to treat and increasing the risk of disease spread, severe illness, and death. Once considered miracle drugs, antibiotics ...

Engineered bacteria reprogram tumor macrophages and direct copper into cancer cells, triggering cell death and systemic immunity without damaging healthy tissue. (Nanowerk Spotlight) Tumors do not ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a team of ...