Science Daily

Th1/17 hybrid T cells offer potent and durable anti-tumor response in preclinical model

Adoptive cell therapy for cancer involves harvesting T cells from a patient and expanding and sometimes modifying them in the laboratory before reinfusion. It has been challenging to create T cells ...
ascopubs.org

TH1/17 hybrid CD4+ cells in bronchial alveolar lavage fluid from leukemia patients with checkpoint inhibitor-induced pneumonitis.

Validating critical analytical variables of a multiplexed gene expression assay measuring tumor inflammation designed to predict response to anti-PD1 therapy. This is an ASCO Meeting Abstract from the ...
Nature

Th1 and Th2 Chemokines, Vaccine-Induced Immunity, and Allergic Disease in Infants After Maternal ω-3 Fatty Acid Supplementation During Pregnancy and Lactation

Chemokines are small chemotactic factors, produced by several cell types, macrophages being an important source (1). Some of them have a crucial role in maintaining the Th1/Th2 balance in immune ...
ascopubs.org

Effect of BCL9/BCL9L inhibition–derived Th1 cells on dendritic cells–mediated antigen presentation in hepatocellular carcinoma and on the efficacy of CAR-T immunotherapy.

Liquid biopsy-based prediction of clinical benefit from immune checkpoint inhibitors in advanced biliary tract cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This ...
The Scientist

Distinguishing Th1 and Th2 Cells

T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...