Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

PI3K/AKT/mTOR pathway blockade with pan-PI3K/mTORC1/2 inhibition produced substantial PFS gains in PIK3CA wild-type disease, addressing an unmet need after CDK4/6 plus endocrine resistance. Adding ...

Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

Each year, approximately 36,000 people are diagnosed with the disease in the United States, according to the American Cancer ...

A leading oncologist reveals science-backed foods that may help lower cancer risk, highlighting how a plant-forward, fiber-rich diet can reduce inflammation and support long-term health.

The mountains, valleys and islands of Washington state are renowned for their natural beauty. But for those dealing with cancer (or trying their best to avoid it!), these magnificent physical features ...

Thirty-six progressive mCRPC patients received TLX591-Tx across three cohorts (enzalutamide, abiraterone, or docetaxel sequence), and all completed two planned doses without emergent, unexpected ...