Rethinking Depression: How Brain “Insulation” Cells Might Hold the Key to New Treatments

A newly discovered mechanism that protects nerve cells could have important implications for understanding and treating ...
Frontiers

Immunometabolism at the crossroads: Metabolic reprogramming and crosstalk in chronic diseases

Immunometabolism has profoundly elucidated the central role of metabolism in regulating immune responses. Metabolism not only serves as the foundation for ...
Nature

Dendritic Cells and T Cell Regulation in Autoimmunity and Transplantation

Dendritic cells (DCs) serve as pivotal sentinels of the immune system, bridging innate and adaptive responses by processing and presenting antigens to T cells. Their inherent versatility enables them ...
Frontiers

Community Series in 'Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics' Volume II

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...
GEN

Efficient T-Cell Transduction and Activation from PBMCs

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.