This figure depicts the complex regulatory network that maintains cellular cholesterol homeostasis. Metabolic and hormonal signals, including oxysterols, IGF-1, and FGF19, activate kinase cascades ...
Plasma LDL-C concentrations can potentially be lowered either by inhibiting the synthesis of cholesterol by the tissues and/or driving the excretion of cholesterol from the body. Although blocking ...
Cholesterol buildup in liver fat droplets directly drives fibrosis in metabolic disease, study finds
Cholesterol plays a vital role in the body, providing structural support to cells and serving as a building block for hormone synthesis. However, when cholesterol accumulates or is improperly ...
Traditional Chinese medicine offers promising natural compounds that modulate cholesterol metabolism, unveiling new therapeutic pathways for cancer treatment. Study: Targeting cholesterol metabolism: ...
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Cholesterol & testosterone: Is there a connection?
This article was reviewed by Felix Gussone, MD. Key Takeaways: Cholesterol is a key building block for testosterone. Through ...
Mutations in LXRα lead to liver cholesterol buildup, hepatitis, and fibrosis in individuals on a Western diet, highlighting the receptor's role in maintaining liver health. Study: Damaging mutations ...
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