Sample sizes for single-stage phase II clinical trials in the literature are often based on exact (binomial) tests with levels of significance (alpha (α) <5% and power >80%). This is because there is ...
Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
When particles in a sample are the same size, one particle can be measured to report the result. If the sample has a narrow distribution, such as 10-25 µm, then measurement of just a few particles can ...
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