Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...

While such advances bring with them a breadth of knowledge, the immense complexity of the datasets makes it challenging for scientists to analyze them using current computational methods. Now, ...