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The DNA Structure That Only Appears When the Cell Is Alive What if DNA doesn’t always look like the classic double helix? Enter i-Motif DNA — a strange, folded DNA structure that forms inside living human cells, but only under very specific conditions. Unlike the familiar double helix, the i-motif twists into a four-stranded knot, held together by interactions between cytosine bases. For years, scientists thought it could only exist in test tubes under acidic conditions — too unstable to survive
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